J.Jpn. Surg. Soc.. 81(9): 1142-1146, 1980
Report on the annual meeting
STUDIES ON PRE- AND POSTOPERATIVE METABOLIC RESPONSE TO PARENTERAL AND ENTERAL NUTRITION IN PATIENTS WITH ESOPHAGEAL CANCER
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Department of Surgery, School of Medicine, Keio University, Tokyo, Japan K. Aoki, T. Kakegawa, M. Endo, N. Ando, Y. Watanabe, A. Oshima, H. Suzuki, M. Hashimoto, H. Otaka, Y. Suguro, H. Miyoshi, Y. Tamura |
In part 1,111 patients were divided into three groups according to real calorie intake/basal energy expenditure ratio; group 1 consists of 15 patients fed by TPN (>1.8×B.E.E.), group 2.26 patients by p.o. (＜ 1.2 × B.E.E.) group 370 patients by p.o. (＜ 1.2 × B.E.E.). The results were as follows; 1, TPN played a role in keeping nonspecific cell-mediated immunity higher than other nutritional regimens. 2, Cardiac Index (Cardiac Output/Body Surface Area) increases significantly in group 1, otherwise no significant differences were found in heart rate, CVP and PWP among three groups.
In part 2, arterio-venous amino acid differences of leg muscle were measured in 20 patients. They were divided into two groups according to the route of nutritional support; group 1 ten patients fed by TPN, group 2 ten patients fed by enteral feeding (ED-AC). The results were as follows; 1, Positive nitrogen balance was obtained by administration of 40 Cal./kg./day in both groups. 2, Decrease of E.A.A./N.E.A.A. molar ratio of arterial blood in group 2 indicates the importance of more investigation about absorption of elemental diet. 3, In high calorie stage of group 1, increased uptake of the branched-chain amino acids to muscle suggested the promotion of muscle protein synthesis.
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