J.Jpn. Surg. Soc.. 81(6): 562-574, 1980
Original article
CLINICOPATHOLOGIC STUDIES FOR PANCREATICODUODENAL CANCER
－OBSERVATIONS FOR FACTORS INFLUENCING PROGNOSIS
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The First Department of Surgery, Tohoku University School of Medicine, Sendai, Japan (Director: Prof. T. Sato) Hohi Ka, Seiki Matsuno, Noboru Noto, Yoichi Saitoh |
1) Five-year survived rates were 14.3% for carcinoma of the head of the pancreas; 17.4% for carcinoma of the intrapancreatic portion of the common bile duct; 38.5% for carcinoma of the Ampulla of Vater. 2) Histopathologically, the poorly differentiated adenocarcinoma in the head of the pancreas, intrapancreatic portion, also in the Ampulla of Vater showed short survivalp eriods. 3) INF in the head of the pancreas and intrapancreatic portion assumed to be closed relation with shorter survival periods of 7.9 and 17.4 months. 4) A factor of cancer invasion into vein in the head of the pancreas or invasion into duodenum or pancreatic parenchyma in the intrapancreatic portion were evidently affected the survival periods. 5) The cancer invasion to the pancreatic capsule apparently in the head of the pancreas or in the intrapancreatic portion with survival periods of 9.2 months, 14 months were significantly short. 6) The survival periods were evidently affected by presence of lymph node metastasis in all portion, especialy in the carcinoma of intrapancreatic portion of the common bile duct. Most of the patients with lymph node metastasis died within 2 years by recurrent cancer.
In view of the factors influencing prognosis of pancreaticoduodenal cancer, the most important factor was the pancreatic capsular invasion.
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