[Abstract] [Full Text PDF] (in Japanese / 2520KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 80(11): 1313-1317, 1979


Report on the annual meeting

MALIGNANT TUMORS IN INFANTS AND CHILDREN

The First Department of Surgery Hokkaido University School of Medicine, 

J. Uchino,  et al.

In spite of much improvement in prognosis of nephroblastoma and rhabdomyosarcoma, the survival rate is still low in patients with neuroblastoma and adult type hepatoma. Clinical and experimental studies on neuroblastoma, hepatoma and nephroblastoma were reported.
Fifty nine patients with neuroblastoma were treated. The 2 year survival rate was 30.4%. While 70% of the stage IVS patients are surviving, the survival rate is only 3.6% in the stage IV patients.
High dose cyclophosphamide and/or papaverine treatment were administrated in 14 patients. Maturation of neuroblastoma cells was not obtained, but a marked decrease of the tumor size was observed in almost all patients. The primary tumors were resected completely in 7 of the 10 patients after CPM treatment.
Twent teryhe patients with hepatoma were treated. Two of the he! atoblastoma patients survived over 2 years, but 7 patients with adult type hepatoma all died within one year.
As the prosnostic factors in neuroblastoma and nephroblastoma, the catecholamine granules and sarcomatous patterns were discussed.


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