J.Jpn. Surg. Soc.. 80(11): 1072-1075, 1979

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Report on the annual meeting

FACTORS INFLUENCING THE IMPROVED RESULT OF CADAVERIC RENAL TRANSPLANTATION

We have performed 41 cases of cadaveric renal transplantation since the first case in 1967 till April, 1979. Both of the functioning graft survival and patient survival rate are remarkablly improved when the result of 21 cases operated during recent 6 years is compared with that of 20 cases operated during early 6 years. Actual patient survival rates of early 20 cases are 45% at 1 year and 25% at 5 years after transplantation, whereas actuarial survival rates of recent 21 cases are 100% at 1 year and 82.5% at 5 years after transplantation. Actual functioning graft survival rates in the early cases are 45% at 1 year and 15% at 5 years, whereas actuarial functioning graft survival rates in the recent cases are 63.2% at 1 year and 33.8% at 5 years after transplantation. Factors influencing the improved result of recent 21 cases are analysed on the basis of frequency of acute tubular necrosis of transplanted kidneys, doses of immunosuppressants, HLA matching, and stimulation index of mixed lymphocyte culture reaction. The result shows that HLA matching is an important factor for graft survival.

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