J.Jpn. Surg. Soc.. 80(11): 1040-1044, 1979
Report on the annual meeting
CLINICAL ASPECTS OF ZOLLINGER-ELLISON SYNDROME
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First Department of Surgery, Tokyo Medical and Dental University, School of Medicine Kazuo Hoshi, Kunio Sugihara, Kimiya Takeshita |
1) No patients presented with steatorrhea in our series and also the site of gastroduodenal ulcers were rather "usual site" in most instances. It seemed to be a conspicuous difference from the cases reported in the english literature.
2) It was found that a large dosis of secretin was sometimes necessary for enough stimulation, probably because of inpurity of secretin product. Purified secretin should be required for reliable and reproducible examination.
3) Preoperative angiography was quite important for localization of gastrinoma, since intraoperative search for the tumor was extremely difficult.
4) Total gastrectomy is a principle management but an emergent operation should be avoided in a poor-risk patient with an adequate medical management.
5) Serum gastrin assay is of a primary importance for detection of Zollinger-Ellison syndrome and moreover secretin test should be added in case of suspicion. It is our suggestion that with a combination of these tests, more patients with Zollinger-Ellison syndrome will be detected.
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