J.Jpn. Surg. Soc.. 80(11): 973-977, 1979
Report on the annual meeting
CARCINOMA OF PANCREATODUODENAL REGION
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2nd Department of Surgery, Nagasaki University School of Medicine, Japan Ryoichi Tsuchiya, Tsukasa Tsunoda, Takatoshi Noda |
Of the 40 patients, 20 with carcinoma of the ampulla of Vater and 9 with carcinoma of the intrapancreatic portion of the common bile duct had pancreatoduodenectomy (P-D), and 11 with carcinoma of the head of the pancreas had P-D (8 cases) and total pancreatectomy (3 cases).
The resectability rate of these patients was 100%, 90% and 35.3%, and the five year survival was 27.3%, 25% and 0, respectively.
A pathological analysis was, therefore, done of 10 patients with carcinoma of the head of the pancreas who underwent curative operations, and revealed the results as follows:
1) The disease spreaded outside the pancreas in all patients except one.
2) The one patient with P-D died four years after operation as a result of multicentric recurrence of remaining pancreas.
3) Carcinoma was left at the line of pancreatic resection in one patient with P-D.
4) In one patient with total pancreatectomy, a skipping lesion was present within the distant area of the pancreas from the principal lesion.
Based on these findings, it is theoretical that patients with carcinoma of the head of the pancreas in early stage should have total pancreatectomy.
In order to detect early carcinoma of the pancreas, combined use of endoscopic aspiration biopsy and serum glycoprotein test should be indicated.
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