J.Jpn. Surg. Soc.. 80(10): 887-901, 1979
Original article
HISTOPATHOLOGICAL STUDY OF INTESTINAL METAPLASIA OF POSTOMORTEM STOMACH IN THE AGED
|
Department of Surgery I, School of Medicine Gunma University (Director : Prof. Takuji Nakamura) Gen-ichi Nakano |
Histopathological study was carried out on 422 stomachs in the aged, obtained at autopsy inTokyo Geriatric Hospital during from 1957 to 1969. Characteristics of this study was that many stomachs of the aged were examined in entire stomach from cardia to pylorus. The cardiac region was not sufficiently examined on previous report because almost all of the former studies were performedon the surgically resected stomach without cardiac region.
Results of this study were as follows:
1) The intestinal metaplasia were classified into six types according to the pattern of distribution;the antral type, the intermediate zone type, the cardiac type, the cardiac & antral type, the diffuse type and the non metaplastic type. The diffuse type was increasing gradually with age, even so the non metaplastic type was found in 10% in every decades older than 60 years.
2) Two spreading patterns of the intestinal metaplasia were observed, the one of them was that the metaplasia occured at prepyloric area spreading to cardia, the other was the fusion of two metaplastic processes occurring at cardia and prepyloric region separately.
3) The intensity of intestinal metaplasia was the highest at the lesser curvature, and no difference of intensity between the anterior and the posterior wall.
4) The intestinal metaplasia occurred primarily at cardia in 7.8% of all cases. The intensity of the intestinal metaplasia at cardia was slightly greater than that at prepyloric antrum. No correlation was recognized between the intensity of the metaplasia at cardia and the grade of atrophic change of the cardiac glands.
To read the PDF file you will need Adobe Reader installed on your computer.