J.Jpn. Surg. Soc.. 80(9): 828-840, 1979
Original article
CLINICAL STUDIES ON THE AMYLASE CREATININE CLEARANCE RATE% (CAm/Ccr)
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Second Department of Surgery, Tokyo Medical and Dental University (Director : Prof. Kenichi Asano) Toshiro lchikawa |
The result is as follows:
1) The Hyperamylasemia which was prominent in the Pancreatic Type Amylase (P-Am) was recognized in the cases of acute and chronic pancreatitis and pancreatic carcinoma.
2) After performing gastrectomy, resection of the colon or cardio surgery, 70-80% of the patients proved to have Hyperamylasemia. Salivery Type Amylase (S-Am) was highly prominent in 71.4-75% of the patients with the Hyperamylasemia.
3) Nine cases out of the eleven acute pancreatitis (82%) and four out of twenty-five non-pancreatic hyperamylasemia (16%) and in these thirteen cases the CAm/Ccr level was over five.
4) An increase in the rate of CAm/Ccr was recognized in the cases of gastric and duodenal ulcer and parotitis as well as acute pancreatitis. It was also in the postoperative conditions of gastrectomy, resection of the colon and cardio surgery.
5) The fluctuation of CAm/Ccr did not run parallel with the serum P-Am and Ccr.
6) There was significant relationship among CAm/Ccr, Serum-α1-Antitrypsin and Serum Lipase.
7) I measured the rate of IgG Creatinine Clearance and Transferrin Creatinine Clearance and found that they increased proportionary to the rate of CAm/Ccr in the acute pancreatitis and the postoperative condition of gastrectomy. As the result it is possible to surmise the fact that both increases were caused by the increse of the glomerular filtration rate.
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