J.Jpn. Surg. Soc.. 80(8): 748-762, 1979
Original article
STUDIES OF BLOOD COAGULABILITY ON PATIENTS WITH CHRONIC ARTERIAL OCCLUSIVE DISEASES
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First Department of Surgery, Gifu University School of Medicine (Director : Prof. K. lnada) Jinzo Fukuda |
1. Hypercoagulability and increase of heparin tolerance were found in patients with any one of these three diseases.
2. Decrease of antithrombin III was more prominent in serum than in plasma in patients with any one of three diseases.
3. Heparin neutralizing substances and the fourth factor of thrombocyte were considered to play an important role for increased heparin tolerance in three diseases.
4. Heparin tolerance was related to coagulation system in Buerger's disease, while it was related to plasma lipoprotein in arteriosclerosis obliterans, suggesting different mechanism between them.
5. Antithrombin III was considered to play an important role as an inhibitor to thrombus formation during postoperative period of reconstructive surgery on patients with Buerger's disease and arteriosclerosis obliterans.
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