J.Jpn. Surg. Soc.. 80(2): 133-140, 1979

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Original article

HEMODYNAMIC STUDY IN CHRONIC PERIPHERAL ARTERIAL OCCLUSIVE DISEASE OF THE LOWER EXREMITIES
―With Reference to Relationship Between the Muscle Blood Flow and the Ankle Pressure in Legs―

In a series of twenty-eight patients (43 limbs) with peripheral arterial occlusive disease, the systolic blood pressure at the ankle (ankle pressure) measured by plethysmographic method and the anterior tibial muscle blood flow by ¹³³Xe clearance method were simultaneously measured before and after exercise.
It was revealed that there was a strong inverse relationship between the post-exercise ankle pressureand the muscle blood flow in the occlusive limbs. However, in the normal limbs there was no change of the ankle pressure with marked increase of the muscle blood flow after exercise.
In a series of forty-three limbs, five types of post-exercise pressure-flow patterns were observed. In Type 1, although the pressure index (ankle pressure/systemic pressure) was less than 1.0, the ankle pressure change and flow pattern response to exercise were similar to those seen in a normal extremity. In contrast with Type 1, the Type V of pressure-flow pattern showed a slight increase of the muscle blood flow after exercise with a marked drop of the post-exercise ankle pressure followed by delayed recovery to the pre-exercise level.
Post-exercise pressure-flow patterns correlated well with the severity and extent of the arterial ocelusive disease.

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