J.Jpn. Surg. Soc.. 79(10): 1324-1334, 1978

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Original article

A SOLUBLE INTERNAL SPLINT FOR VESSELS ABOUT 1 MM IN EXTERNAL DIAMETER IN EXPERIMENTAL VASCULAR ANASTOMOSIS

We have developed a technique of Non-suture vascular anastomosis which is based on the use of water soluble splints and plastic adhesive. This is easy to apply, save time and does not require any large complicate instruments. Already we succeeded in the anastomosis of vessels exceeding 2 mm in external diameter, therefore, we challenged smaller vessels by improving the water soluble splints.
The soluble splints were 0.6 to 1.6 mm in diameter and stick formed. These made of 85% saccharose, 14% P.V.P. and 1% polyethylen-glycol. The dissolution time of this splint was within 2 minutes. Adhesive was alpha-ethylcyanoacrylate monomer. End to end arterial, end to end autogenous venous grafting anastomosis and end to side autogenous venous grafting anastomosis were performed using vessels of rats (about 1 mm in external diameter).
Anastomosis was observed angiographically as well as macroscopically and microscopically. Strength of the anastomosed portion was examined by pressure durability and traction durability test.
The patency rate of the end to end arterial anastomosis was 87.2%. End to end venous grafting was 81.5% . End to side venous grafting was 50%.
If several problems are solved, it can be applied practically, for example elasticity, softening of the adhesive, control of the soluble time.

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