J.Jpn. Surg. Soc.. 79(9): 1002-1007, 1978

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Report on the annual meeting

COMBINED THERAPY ON ADVANCED SOLID TUMOR IN PEDIATRIC AGES, ESPECIALLY WITH RADIOTHERAPY

We had the privilege of participating in the irradiation therapy in the NIRS ourselves since 1970. We gave chemotherapy and performed follow-up studies ourselves as well. The treatment results in this treatment system after 1970 have been greatly improved. Multiple course of Actinomycin D, started to be given since 1970, would be one of the other reasons of this improvement.
The treatment method in combination with radiotherapy and treatment result in our series of cases were discussed here.
On Wilms' tumor, all of 13 cases were dead in 3 years in the period before 1969, while all except one case of Stage IV and one case of advanced Stage V have been alive in the period after 1970.
In the treatment plan, the microscopical findings must be evaluated in addition to the usual macroscopical surgical staging, especially Stages I and II. In the radiation treatment of pulmonary metastasis of Wilms' tumor, radiation therapy must be the first choice, and then chemotherapy followed. Radiation effect is always far greater than chemotherapy.
We succeeded in the treatment of 2 cases of Stage III dysgerminoma, with extirpation followed by whole abdomen irradiation. Radiation therapy was effective and curative on this tumor in the advanced stage.
We had 3 cases of long term survival among 7 cases of advanced rhabdomyosarcoma. Radiation therapy are not effective enough to cure this tumor in the limited dosis. Massive chemotherapy must be followed.

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