[Abstract] [Full Text PDF] (in Japanese / 1623KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 79(8): 823-827, 1978


Report on the annual meeting

SURGERY FOR LUNG CANCER AND ADJUVANT IMMUNOTHERAPY

Department of Chest Surgery, Kyushu Cancer Center

Mitsuo Ohta

Immunotherapy with BCG-CWS was applied to 155 lung cancer patients after usual modalities of treatments.
Prolongation of survival periods was revealed after BCG-CWS treatment in each clinical stage of lung cancer. In resected cases the survival rate of control patients and BCG-CWS treated patients were 28% and 61% respectively at 36 months (p value<0.001).
In vitro lymphocyte responses which were assessed later than 4 months after the start of BCG-CWS treatment correlated well with the prognosis of patients.
Pathological examination of autopsied cases suggested that BCG-CWS treatment not only suppresses hematogenous metastases but also augments resistance against microorganisms.
Immunotherapy would seem to be most appropriate as an adjuvant modality following resectional surgery for lung cancer.


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