J.Jpn. Surg. Soc.. 79(1): 42-56, 1978
Original article
STUDIES ON POSTOPERATIVE BLOOD PRESSURE RESPONSE IN RENOVASCULAR HYPERTENSION RELATING WITH PATHOPHYSIOLOGICAL BEHAVIOR OF THE AFFECTED KIDNEY
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Department of Thoracic Surgery, Faculty of Medicine, University of Tokyo (Director: Prof. Masahiro Saigusa) Hiroshi Inoue |
1. Ischemic changes such as mural thickening of arteriole, atrophy of tubulus, interstitial fibrosis and cell infiltration, hyalinization of glomerulus and hyperplasia of juxtaglomerular apparatus were observed in all 42 histological specimens of the renal tissue distal to the arterial stenosis, and 7 cases, in which severe ischemic changes were observed, did not attain the patency of reconstructed renial artery.
2. The PRA value shifted in a specific pattern after successful sugery, i.e., transient high value occurred immediately after surgery, and returned to normal value within a week.
3. In regard to the PRA value which was measured at the time of surgery, the ratio of renal vein PRA value in the kidney with stenosed artery as compared to that in the opposite one exceeded 1.5 in successfully operated cases, and furthermore, the renal vein PRA value of the kidney whose renal artery was stenosed exceeded 50ng/ml/hr.
4. Concerning the length of the longitudinal axis of the kidney, the axis of the affected kidney was apparently shorter than that of the opposite in preoperative period, but after the successfully performed surgery it increased in length, and we could not find any difference between them with mean follow up period of 7 years.
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