J.Jpn. Surg. Soc.. 78(12): 1191-1199, 1977

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Original article

THE CLINICAL SIGNIFICANCE OF HYPERAMYLASEMIA FOLLOWING ABDOMINAL TRAUMA

Hyperamylasemia was found in 15 (65.2%) of 23 patients with abdominal trauma. We found that the serum amylase level was elevated even in the cases without pancreatic injury. In this study, we evaluated the serum amylase activity, origins of amylase in abdominal trauma patients and mechanismus of hyperamylasemia.
1) Serum amylase activity level was closely related to shock duration in abdominal trauma as well as severe trauma patients.
2) Isoamylase pattern seen in abdominal trauma was that of salivary type except for pancreatic injury.
3) Since amylase clearance was all within normal range, macroamylasemia or renal failure as the cause of hyperamylasemia was denied.
4) It is difficult to think that amylase leak out into circulation from cytoplasma by hyperpermeability of cell membrane or by cell destruction following hyperpermeability of cell membrane.

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