J.Jpn. Surg. Soc.. 62(7): 667-693, 1961

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GENERAL HYPOTHERMIA AND ARTRIFICIAL HIBERNATION AND RELATIONSHIP OF GENERAL HYPOTHERMIA TO SURGECAL SHOCK. (EXPERIMENTAL STUDY ON TISSUE OXYGEN CONSUMPTION)

General hypothermia and artificial hibernation, and relationship of general hypothermia to surgical shock are studied on tissue oxygen consumption of animal organs using Warburg's manometric method. The results are as follows:
1) .As body temperature is lowered, every organ except skeletal muscle reacts to consume more oxygen than normal tissue in same temperature. Below 25°C. this reaction stops.
2) Qo₂ of the central nervous organs is decreased and that of the lung increased by Wintermin.
3) In early stage of burn shock Qo₂ of the central nervous organs is characteristically increased, while this reaction is not so increased by additional hypothermia.
4) In the early stage of heamorrhagic shock Qo₂ of the liver and splean is decreased, while above reaction is not so decreased by additional hypothermia.
5) .Qo₂ of the liver is increased by serum of shock animal and artificial hyperthermic animal, but not increased by hypothermic serum.
(Author's abstract)

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