J.Jpn. Surg. Soc.. 61(2): 185-209, 1960
STUDIES ON THE SPREADING AND PREVENTION OF STAPHYLOCOCCI IN SURGICAL CLINICS
ーOBSERVATION FROM THE VIEW POINT OF THE RELATIONSHIP WITH ANTIBIOTIC THERAPIESー
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Nakayama's Surgical Department, Chiba University School of Medicine (Director: Prof. Komei NAKAYAMA) Yoji IWASAKI |
The rate of the staphylococcal isolation showed various values from 31 to 77 per cent. In our surgical clinic, in which the largest amount of antibiotics had used, the highest rate appeared among the four clinics.
The spreading of staphylococci, especially those resistant to antibiotics, is extremely well promoted by the use of antibiotics.
2) Most of the staphylococci isolated in our clinic were different from other clinics in phage typing and some of them belonged to a group which might be called " hospital staphylococci " .
3) It was proved, using mehtod of phage typing, that staphylococcal dissemination was frequently seen among patients, doctors and nurses.
Cases of cross-infection were also observed among patients.
4) Clinical features of staphylococcal infection among postoperative patients, and the cause of postoperative enterocolitis are discussed.
5) Experimental and clinical studies on the prevention of staphylococcal spreading were carried on mainly concernig the use of antibiotics for patients operated on for diseases of digestive tract.
According to the rate which staphylococci acquire resistance to antibiotics in vivo and the effects of antibiotics on the organ distribution and the hemolytic activity of staphylococci injected into the abdominal cavity of mice, the fact that the continuous use of one antibiotics over 5 days is rather injurious for the prevention of postoperative infection has been proved.
6) Schedule of the use of antibiotics for postoperative patients has been devised on the basis of the results from these results.
(Author's abstract)
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