[Abstract] [Full Text PDF] (in Japanese / 12850KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 61(1): 1-11, 1960


STUDIES ON HOMOLOGOUS SKIN TRANSPLANTATION
I. ON EXPERIMENTS UNDER INHIBITED REACTION

Department of Surgery, Faculty of Medicine, Tohoku University, Sendai. (Director: Prof. S-T. KATSURA)

Sakari SATO

Experiments on homologous skin transplantation in mice were conducted aiming at long survival of the graft under inhibition of transplantation reaction and the following results were obtained:
1. Use of fetal skin for the graft does not lengthen the time of survival.
2. Use of grafts of skin irradiated with ultraviolet ray, refrigerated skin or skin from donor exposed all over to X-ray does not lengthen the time of survival.
3. So-called immunological paralysis by injection of skin extract, homogenate and crude polysaccharide fractions extracted from the skin or the spleen was induced, but this mothod failed not only in lenthening the survival time, but also in shortening it by the produced immunization.
4. Splenectomy applied to the recipient showed no effect on the result of transplantation.
5. General X-ray irradiation of the recipient caused no very perceptible lengthening of the survival time, not beyond 22 days at the ulmost.
6. No specific finding was observed by application of any of the above treatments in the histological pictures at the time of necrosis and rejection of the graft.
(Author's abstract)


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