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J.Jpn. Surg. Soc.. 60(3): 427-448, 1959


A STUDY ON THE INTESTINAL DIGESTION AND ABSORPTIVE FUNCTION FOLLOWING VARIOUS GASTRECTOMIES

Nakayama's Surgical Clinic, Chiba University Medical School (Director : Prof. Komei NAKAYAMA)

Kazutosi HIROTA

The evaluation of the intestinal digestion and absorptive function after various gastrectomies was made chiefly with the Cr2O3 ratio method on adult dog and man. The followings are chief conclusions :
1) Following the Billroth I. type gastrectomy, the protein and fat absorption rate was reduced in protortion to the size of resection especially by protein markedly, and when surpass 70% of the entire surface area the reducing was roughly, while the fecal excretion of carbohydrate was within the normal range regardless of the size of resection.
2) Cardiectomy or segmental resection of the body of the stomach showed less diminution of protein and fat absorption rates than pylorectomy of equal size.
3) The Billroth I. type reconstruction mode was found to produce better absorption rate in both protein and fat than the Billroth II, type, and this tendency appeared more prominently in fat.
4) The contact of food with the gastric mucosa and its passage through the duodenum must be stimultaneously met for favourable digestive activities. Lack in either element causes marked reduction in absorption.
5) The antrum and pyloric ring were found as more significant part to reserve digestive and absorptive function than hither to believed.
6) These evaluation was examined by the Cr2O3 ratio method, which the author and cooperators established in the surgical-medical field, that permits observation of absorptive rate on each defecations, and these evaluation was also confirmed by the observation of the transition of intestinal absorptive rate, which we applied ratio method to various segment of the canine intestine.
7) Operative intervention to the canine gut brings more serious impairment of digestion than it does to humans, but the tendency is similar.
(This work was partly presented by Prof. Nakayama at the Anniversary Congress in 1958, by honorable request of the Japanese Surgical Society)
(author's abstract)


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