J.Jpn. Surg. Soc.. 60(1): 30-45, 1959

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IRON METABOLISM IN PATIENTS WITH GASTRIC CANCER AND DUODENAL ULCERS
REPORT II. RESULTS OF PERORAL IRON LOADING BEFORE OPERATION

The author carried out peroral loading tests by the use of reduced iron in 17 patients with gastric cancer and 21 cases of ulcers of the stomach and duodenum, a total of 38, selected from 520 patients with these conditions admitted to the care of Professor Matsukura's Department of Surgery, during the period of 3 years (January 1954-December 1956). The state of iron absorption was evaluated from the absorption curves and its relation to clinical findings was examined from various angles. Some of the conclusions may be summarized as follows :
1) Generally speaking, the state of iron absorption in patients with gastric cancers is extremely poor, although a few cases showing marked gastric hemorrhages gave high iron absorption rates. This tendency particularly marked in patients with serious systemic manifestations associated with passage disturbances of the stomach and pylorus.
2) Iron absorption is remarkably high, as compared to normal individuals, in the patients with gastric and duodenal ulcers associated with gastri hemorrhages and those with slight complications and mild systemic involvement. On the contrary, the absorption is poor in patients with disturbances of gastric and pyloric passage, and this more pronounced, when the symptoms are more marked.
(author's abstract)

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