J.Jpn. Surg. Soc.. 59(10): 1630-1638, 1959
STUDIES ON SODIUM ALGINATE OF LOWER POLYMERIZATION, A PLASMA EXPANDER
II. DETERMINATION OF OPTIMAL CONCENTRATION OF SALT IN THE SOLVENT OF ALGINATE SOLUTION
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Department of Medical Chemistry, Faculty of Medicine, Kyushu University, Fukuoka (Director: Dr. R. Hirohata) Ryuzaburo INOUE |
1) In cases supplied 4.5 g of NaCl per day, salt deficit was observed from the in-and out-take balance of NaCl, salt concentration in urine and serum, whereas in cases supplied 9 g of NaCl per day, salt retention was observed, though salt concentration in urine and serum were maintained. It was asssumed that salt balance during 48 postoperative hours was maintained by supplying salt balance during 48 postoperative hours was maintained by supplying salt 6-7 g per day.
2) Concentration of NaCl in the alginate solution as a plasma expander was decided as 0.3%, considering that the maximum dose of alginate solution in a day was approximatly 25 cc per kg of body weight, and the amount of salt supply per day was 4.5 g. This decision was made from the consideration that slight deficit of salt (4.5 g per day) was rather preferable to excess supply in immedediate postoperative days, and 4.5 g per day of salt supply met to this opinion.
3) In cases of no salt supply with glucose supply of 0- 25 g per day, chloride concentration in red cell in postoperative 24 hours increased higher than the preoperative values. On the contrary, in cases of 9 g salt supply per day and of 50 g glucose supply per day chloride concentration in red cell decreased. Based on these data, the supplying conditions of glucose in postoperative patients were discussed.
(author's abstract)
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