J.Jpn. Surg. Soc.. 57(7): 1225-1240, 1956

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AN EXPERIMENTAL AND CLINICAL STUDY ON THE ABSORPTION OF THE INTESTINE IN CASES OF POSTLAPAROTOMY, ACUTE PERITONITIS AND INTESTINAL OBSTRUCTION

The author has made a study of early postoperative feeding using the radioactive isotope P³² in a double lumen tube in order to find out whether these early feedings are well absorbed or not, which is a very important question.
Twenty-nine rabbits and 38 human cases of postlaparotomy, peritonitis, intestinal obstruction were observed for absorption of P³² in the blood and urine, and we have come to the following conclusions.
1) Compared to controls, in rabbits with peritonitis, the absorption of P³² decreases as administration is prolonged after the onset of the disease.
2) When rabbit's intestine is ligated and P³² administered in both the oral and anal sections, the absorption of the isotope is greater in the anal section.
3) P³² was administered 6 hours after gastrectomy to patients with gastroduodenal ulcer and gastric cancer. The date of absorption was the same as in controls. There was a decrease of absorption in cases of peritonitis, where appearance of P³² in the blood, concentration in the blood and amount excreted in the urine showed that the absorption is definitely lowered. It was found that the absorption of P³² given early after gastrectomy was very good.
After gastrectomy it is believed that the absorption returns to normal at an early stage.
(author's abstract)

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