J.Jpn. Surg. Soc.. 56(10): 1339-1356, 1956
EXPERIMENTAL AND CLINICAL STUDIES ON THE URETERAL TRANSPLANTATION USING CHIEFLY ARTERIAL GRAFTS PRESERVED IN ALCOHOL
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Depertment of Surgery, Tokyo Medical College (Director: Prof. Kingo SHINOI) Mitsuma KODAMA |
1) Materials :
The materials for transplantation were arteries preserved in 70 per cent alcohoI solution from dogs and horses in most cases. The fresh materials are autoplastic or homoplastic fallopian tube, fascia, skin, bile-duct, vein and artery. It was demonstrated that the materials preserved in alcohol among other materials showed the best results for the ureteral transplantation.
2) Post transplantation stenosis of the ureter and its preventive measures :
A large number of dogs occurred the postoperative stenosis within two or three weeks after transplantation especially in the groups used fresh materials. For the preventive measures of the postoperative stenosis, the insertion of vinyl tube into the graft, as a splint, was exceedingly effective. This procedure was successfully in my experimental and clinical uses.
3) Fate of the grafts :
The replacement phenomenon by the granulation from the surrounding tissues was observed on the transplanted area within 4 weeks after operation, the organization and epithelization was completed and then the new ureter was formed. Elastic fibers of the artery may play an important role of reinforcing for new formed ureter without being absorbed for relatively longer period. This fact shows the characteristics of the arterial grafts as materials for transplantation.
4) Clinical experience :
The author attempled to apply this ureteral transplantation described above in the patient suffering from the cancer of the ureter. It is evident that the clinical purposes of transplantation were accomplished sufficiently, although this patient died of the cachexy within 6 weeks postoperatively.
(author's abstract)
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