J.Jpn. Surg. Soc.. 56(7): 920-929, 1955

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EXPERIMENTAL STUDIES OF EPILEPTIC SEIZURE ON THE BASIS OF "MARCH OF MOVEMENT"
Ⅳ. THE INTERPRETATION OF EPILEPTIC SEIZURE DEMONSTRATED IN "MARCH OF MOVEMENT"

In addition to the author's three previously published arlicles the following test has been performed as to more detailed aspectes of the march of movement of epileptic seizure.
(1) By strong stimulation on the cortex, nucleus lentiformis or thalamus, homophasic convulsive seizures can be produced. There is evidence that the development of varying aspects of convulsive seizures influenced by the exsistence or non-exsistence of the motor area in the case of slimulation of the midbrain. This can be interpreted by the fact that the motor nuclei, which contribute to convulsion are related to each other, and cause convulsive seizure in a continuous ascending scale by reverberation.
(2) Status convulsivus shows many varieties of the mode of a consecutive convulsive seizure. A series of convulsive seizures produced by repeated electrical stimulation shows varying aspects of convulsion resulting in cessation, in spite of a unified intensity of stimulation So-called facilitation and fatigue can be observed even in convulsion.
Thus it is assumed that various modes of convulsion are attributable to the changes in excitability of the cerebrum.
(author's abstract)

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