J.Jpn. Surg. Soc.. 56(3): 283-293, 1955
CLINICAL AND EXPERIMENTAL STUDIES UPON THE FLUIDTHERAPY IN THE SURGICAL PATIENTS
PART 1: FUNDAMENTAL AND CLINICAL STUDIES ON THE DETERMINATION OF THE BODY FLUID
|
Surgical Department of Sagamihara National Hospital (Director: Soiti YANAGI and Tosio TAKAFUZI) Goro MIZUKAWA |
In this report, the author has described the studies on the total body water volumes, and their clinical considerations.
About the former, have been reported the historical notes on the total body water determination, the methods or technics, the data obtained, comparing with the physical findings of surgical patients. As the technic estimating the total body water volume, has been adopted the antipyrine-methode described by Soberman, 1948. But this method was too complicated for the clinical use, and so the author has tried to simplify it.
The conclusions resulting from these data are following.
As the most important factors of this antipyrine method, must be considered the temperature and the elapsed time. The temperature was 37°C, the time was 30 minutes and 2 blood samples have been found enough and adequate. About other factors, e.g., the extrapolation, the density, the calculation of infused antipyrine concentration and the water contents of plasma, some experiments have been tried.
It must be noticed clinically, that the volume of the total body water has been reduced, while that of the extracellular fluid apparantly increased in the dehydrating or hypoproteinemic cases.
The author has also illustrated the fact that the postoperative increase of potassium output in the urine means the secondary intracellular dehydration, one of the dangerous symptoms in the treatment of the surgical patients.
(author's abstract)
To read the PDF file you will need Adobe Reader installed on your computer.