J.Jpn. Surg. Soc.. 55(2): 120-128, 1954
Original article
ON CHANGES OF WATER CONTENT OF LIVING TISSUE CAUSED BY SODIUM ALGINATE
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2nd Surgical Clinic, Faculty of Medicine, Kyushu University (Director : Prof. M. Tomoda) Hideo MATSUBAYASHI |
1) The volume of circulating blood-plasma increased by the injection and the length of time in which it was retained in the blood vessel were greatest and longest when the liquid which was injected was blood serum, and gradually reduced when it was a 0.3% saline solution of sodium alginate and physiological saline solution. The increase after the injection in the water content of skin tissue was smallest when injected liquid was blood serum, and gradually larger when it was a 0.3% saline solution of sodium alginate and physiological saline solution.
2) No definite relation was seen between the change after the injection in the water content of muscular tissue and the liquid injected, presumably because the water content of muscular tissue was affected to no small extent by the amount of urine excreted by the animal.
3) Generally speaking, the amount of urine during 12 hours after the injection of the three kind of liquids, was great in the rabbits which were injected with blood serum or physiological saline solution, and small in those which were injected with 0.3% physiological saline solution of sodium alginate.
The foregoing experimental results, indicating that a 0.3 % saline solution of sodium alginate penetrates the wall of a blood vessel less easily and is excreted in urine with greater difficulty than physiological saline solution, make it conceivable that this is one of the reasons why the increased amount of circulating blood-plasma was long kept up in the rabbits after the injection of the former solution. (author's abstract)
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