J.Jpn. Surg. Soc.. 54(11): 999-1008, 1954

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Original article

STUDIES ON THE PATHOGENITY OF BACTERIA
Part I. The Pathogenity of Staphylococci

Studying experimentally about correlation between pathogenic bacteria and reaction of the invated tissue, as a factor to alter the concentration of the agent in focus, when we administer chemotherapy, the results were as follows.
(1) Investigating hemotoxin, staphylocoagulase, hyaluronidase, fermentation of lactose and mannitol, staphylolysin, anticoagulant and pathogenity upon the skin of rabbits, of many kind of staphylococcus as a pathogenic bacteria, the strains which produced staphylocoagulase and hyaluronidase caused inflammation on the skin of rabbits.
(2) There were hyaluronidase-positive staphylococci on a markedly reddened lesions or celluritis.
(3) There were on specific relationship between the sensitivity to penicillin, aureomycin and terramycin, and the production of staphylocoagulase and hyaluronidase.
(4) Spreading factor and inflammation of staphylococci were controlled by the injection of Communin.
(author's abstract)

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