J.Jpn. Surg. Soc.. 54(11): 639-647, 1954
Original article
AN EXPERIMENTAL STUDY ON THE CHARACTERISTIC FUNCTION OF THE SPLEEN AS A STIMULUS-INDUCING BODY BY WHICH AN ANEMIA CAUSING ACTIN IS STARTED
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Second Surgical Department, Faculty of Medicine, Kyushu University (Director : Prof. Masanobu TOMODA) Hisashi YOSHITOSHI |
I) The spleen subjected to X-ray radiation (3,500 r to 6,000 r) loses its function as a stimulus-inducing body by which anemia-casusing action is started, but 6,000 r radiation cannot deprive the organ of its function as a stimulus provoking an anemia-causing action.
II) The occurrence of anemia in the rabbit in consequence of an anemiacausing substance injected into it is only possible when a normal or transplanted spleen exsists in the animal.
However, spleen emulsion injected cannot take the place of a normal or transplanted spleen in causing anemia in this case.
III) In short, the function bf the spleen as a stimulus-inducing body by which an anemia- causing action is started, comes into play only in the presence of normal splenic cells and is never exhibited when the spleen is damaged by X-rays or mechanically.
(author's abstract)
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