J.Jpn. Surg. Soc.. 54(4): 323-333, 1953
Original article
STUDIES ON THE INFLUENCES OF THE SEXUAL-HORMONE UPON MAMMARY CANCER (PART I)
I. THE EFFECTS OF OOPHORECTOMY ON MAMMARY CANCER
|
II. Surgical Department, Tokyo University Yoshiyuki KITA |
I observed, in their clinical courses, the influences of oophorectomy upon the quantity of estrogen in urine, of calcium, inorganic phosphate and alkaliphosphatase in serum, and the following deficient symptoms after oophorectomy,
The results were as follows:
(1) There are some records reporting that the menopause of the patients is mostly delayed, but in my cases, it was just the same as normal conditions, (2) and in 41 of 54 cases, the menses were seen at the time of detection of mammary cancer. Generally mammary cancer rises still in the age in which ovarium has its active function (3)As for the quantity of estrogen in urine, there are little differences between the patients and the healthy women, indicating much differences, in personally than in age, (4) Oophorectomy would have good effects on the patients before menopause, but not on the other patients.
(5) After the oophorectomy, estrogen in urine disappeared except in a few cases, and metastasis to the lymphatic gland and the skin diminished, (6) Oophorectomy brought some deficient symptoms on the patients before menopause, but nothing on the others. (7) On calcium, inorganic phosphate and alkaliphosphatase in serum, there was nothing to report (author's abstract)
To read the PDF file you will need Adobe Reader installed on your computer.