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J.Jpn. Surg. Soc.. 119(3): 266-271, 2018
RESEARCH ON SCIRRHOUS GASTRIC CARCINOMA FROM THE VIEWPOINT OF A SURGEON
I have performed digestive tract surgery for approximately 30 years while continuing research. Gastric cancer has been the condition most frequently encountered. A scirrhous gastric cancer cell line and fibroblasts were established from a case of scirrhous gastric carcinoma in my graduate student era, and I have conducted research on scirrhous gastric cancer for 25 years mainly using those cell lines. We found novel mechanisms of occurrence and are currently associated with clinical studies developed based on the research on scirrhous gastric carcinoma. It is a source of motivation as a surgeon to clarify clinical questions at the laboratory bench level and to feed back the results to the bedside. Surgeons are in a good position to perform translational research. That advantage of surgeons should be utilized in research, and we should maintain a research mindset when attempting to resolve clinical questions.
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