J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 657KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 95(3): 141-148, 1994

Original article

A STUDY OF NOSOCOMIAL INFECTIONS BY THE COMPARISON OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA

1) First Department of Surgery, Hiroshima University School of Medicine, Hiroshima, Japan
2) Department of General Medicine, Hiroshima University School of Medicine, Hiroshima, Japan

Yoshio Takesue1), Takashi Kodama1), Takahiro Santo1), Yoshiaki Murakami1), Atsushi Nakamitsu1), Yuichiro Matsuura1), Takashi Yokoyama2)

The objective of this study was to investigate nosocomial infections by the comparison of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. We made a serological classification of 262 strains of Pseudomonas aeruginosa between 1983 and 1991. Group E strains were prevalent in 1987 and group F strains after 1990. Both these groups strains were resistant to several antibiotics, and were scarcely detected from the appendix contents in appendicitis that originated outside the hospital. Therefore we presumed these were nosocomial pathogenes.
With the countermeasures to nosocomial infections from 1987 on the isolation rate of enterotoxin type B and C MRSA strainsdecreased. Following this MRSA change, almost group E strains disappeared in Pseudomonasaeruginosa. Whereas type AC MRSA began to isolated abruptly from 1990, and the isolation of group F strains increased simultaneously.
Type B and C strains still remained high sensitivity to minocycline. Type AC which have already gotten resistance to minocycline took the place of type B and C and prevalented. Similarly group F in Pseudomonas aeruginosa took the place of group E as soon as the former acquired resistance to carbapenem.

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