[
Abstract]
[
Full Text PDF] （in Japanese / 485KB）
[Members Only And Two Factor Auth.] J.Jpn. Surg. Soc.. 93(2): 133-138, 1992
Original article
RELATIONSHIP BETWEEN VENOUS INVASION AND HEMATOGENOUS METASTASIS IN THE COLORECTAL CANCER PATIENTS
We investigated the correlation between venous invasion and hematogenous metastasis. In thirteen patients with colorectal carcinoma, depth of invasion (ss ・s or a
1 ・a
2) was the same. Four cases had hepatic metastasis at operation (group A), 3 cases were identified with hematogenous recurrence after operation (group B), and 6 cases were disease free over 10 years after operation(group C). Specimens were all step-sectioned and serial sections were stained both with HE and EM. Results were as follows. 1. Venous invasion was found in all cases and average rates of venous invasion (ARVI) of groups A and B were higher than that of group C (A; 7.8%, B; 6.3%, C; 2.1%, p<0.05). 2. In ss ・s layer, ARVI of group A and B were higher than that of group C (A; 6.1%, B; 6.2%, C; 1.5%, p<0.05). 3. Rates of venous invasion to larger veins (diameter>200μm) were higher in group A than in others (A; 53.5%, B; 25.6%, C; 7.9%, p<0.05), and those to the middle-sized veins (diameter; 50～200μm) were higher in group B than in others. These facts suggest that cancer invasion to the veins located in ss ・s (a
1 ・a
2) layer or ranged in diameter over 200μm relates to hematogenous metastasis.
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