[Abstract] [Full Text PDF] (in Japanese / 4572KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 82(10): 1248-1254, 1981


Original article

METHOD OF RADIOIMMUNOASSAY FOR HUMAN ELASTASE 1 AND SERUM ELASTASE 1 LEVELS IN PANCREATIC DISEASE

First Department of Surgery, Osaka City University Medical School

Yoshaku Tei, Katsusuke Satake, Kaoru Umeyama

The radioimmunoassay for human elastase used in this experiment has accuracy, sensitivity and specificity, which have been confirmed by our observation.
In acute pancreatitis, acute relapsing pancreatitis and chronic relapsing pancreatitis, serum elastase 1 levels were higher than normal value. However, serum elastase 1 levels in chronic pancreatitis were within normal limits. In pancreatic cancer, most of patients had greater serum elastase 1 levels than in normal.
In various diseases other than pancreatic disease, serum elastase 1 levels were within normal limits.
Although serum elastase 1 level in hyperamylasemia other than pancreatic origins was slightly higher than normal value, it was not as high as those in acute pancreatitis and relapsing pancreatitis.
These results indicate that the measurement of serum pancreatic elastase by radioimmunoassay is useful for the diagnosis of pancreatic disease.


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