J.Jpn. Surg. Soc.. 82(2): 169-180, 1981
Original article
MICROANGIOGRAPHIC STUDY OF COLORECTAL CENCERS
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The First Department of Surgery, Nagasaki University School of Medicine Takatoshi Shimoyama, Seiji Kitasato, Toshihiko Takagi, Tatsuhiko Nogawa, Tatsuo Hirano, Tatsuro Harada, Chisato Yoshida, Hiroshi Nakayama, Shigehiro Hashimoto, Ryosuke Fujii, Masauki Setoguchi, Yoshihisa Ishikawa, Yasunori Kotake, Toshiyo Ishii, Yuzo Uchida, Toshio Miura, Yasukuni Tsuji |
1. The normal vascular patterns were described. The vascular patterns of malignant lesions were classified into 3 groups: (1) changes of vascular lumen, (2) changes of the directions of vessels, (3) neovascularization.
2. The vascular patterns of hyperplastic polyp and adenomatous polyp resembled the normal mucosa. However, in foci of atypical glandular proliferation within a polyp, the regular arrangement of the vessels had become disorganized.
3. The polypoid cancer had long straight vessels appearing even straighter than the adenoma. Of early elevated cancer (IIa type), the sm cancer presented hypovascular pattern, and the m cancer hypervascular.
4. The advanced cancer of 1 type showed hypervascular patterns and the vascular disarray withvessels of varied size which histological foci of necrosis were often seen. The vascular patterns of 2 and 3 type were classified into 5 subtypes, and has been discussed with degree of cancer invasion, location of tumor and tumor site of lumen.
5. The carcinoma with liver metastasis had vascular disarray with histological foci of necrosis and the changes of vascularity in outside of tumor were recognized.
6. The findings obtained with microangiography correlated well with the histological observations with special reference to interstitial reaction of the carcinoma.
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