[Abstract] [Full Text PDF] (in Japanese / 1750KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 80(12): 1412-1415, 1979


Report on the annual meeting

IMMUNOLOGICAL BACKGROUND OF LYMPH NODE METASTASIS AT SURGICAL OPERATION IMMUNOLOGICAL STUDIES ON REGIONAL LYMPH NODES IN DIGESTIVE TRACT CANCER-

Department of Surgery, Kyoto Prefectural University of Medicine

Masashi Kodama

For several years we have studied the defense mechanism against cancer on the regional lymph nodes in gastric cancer using the macrophage migration inhibition test (MIT) and the mixed lymphocyte tumor reaction (MLTR).
The activity of the lymphocytes in the regional lymph nodes was generally higher than in the peripheral blood lymphocytes in both tests. Activity of the non-metastatic lymph nodes was higher than the metastatic lymph nodes.
In 15 cases of gastric cancer, in which the lymphocytes in both the regional lymph nodes and peripheral blood were measured, 47% showed positive in peripheral blood lymphocytes and 74% showed positive in regional lymphnode lymphocytes.
Seven to 14 days before operation, BCG or BCG-Cell Wall [BCG-CW] vaccine was administered intralesionally using endoscopy.
In 4 cases, it was demonstrated that the activity of MLTR in the regional lymph nodes was elevated.


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