J.Jpn. Surg. Soc.. 80(11): 1067-1071, 1979

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Report on the annual meeting

ORGAN PRESERVATION

To make clear the limit of warm ischemic time (WIT) at the cadaveric organ transplantation, animal experiments at several WIT were carried out on organ temperature, temperature difference between organ and perfusate, flow volume of perfusate, vascular resistence, PH and BE of the perfusate and histological findings using an organ perfusion device (Fukushima Medical School model) and organ perfusion canula (Fukushima Medical School model). Organ perfusion was performed by two methods in which the perfusate consisted of Ringer lactate solution in one group and artificial blood (Fluosol- DA) in the other group. From these results, the limit of WIT was thought to be 30 min.
Recently cadaveric kidney transplantation was performed in two cases (FCK-7, -8) in our clinic in which the donor kidneys were perfused by 10% Fluosol-DA for 131 to 185 min. The urination was recognized at 27 and 37 postoperative days in FCK-7 and FCK-8 respectively. The postoperative courses in both cases were uneventful.

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