J.Jpn. Surg. Soc.. 79(9): 984-989, 1978

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Report on the annual meeting

ANALYSIS OF ADVANCED SOLID MALIGNANT TUMORS IN CHILDREN

A review of 119 cases of solid malignant tumors under 15 years of age, experienced during the past 30 years, confirmed that the 2 years period of tumor free was acceptable as a criterion of cure in pediatric solid malignancy. Therefore 101 cases of 119, up to 2 years before the present study, were chosen as the materials. The localized tumors were in 37, 4 of which progrssed to advanced stage later, and the over all cure rate was 84%. The locally advanced tumors were in 34 and the distantly metastatic or multicentric tumors in 30, and the cure rate was 18% and 5%, respectively.
Eighty-six precent of 35 neuroblastomas were advanced cases, the stage III being 11 with 2 cures and the stage IV 19 with only 1 cure. The value of so-called reduction suregry was not confirmed in the advanced neuroblastoma and the possibility of fair amount of operative reduction rather indicated that the status of the patients was not desperately ill.
It was also suggested that bilateral Wilms' tumor might contain a prognostically favorable group (which might be called as V-S Wilms' tumor) like the stage IV-S neuroblastoma among the stage IV tumor and that those with poor prognosis might belong not to multicentric origin but rather to metastatic nature.

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