J.Jpn. Surg. Soc.. 57(12): 1973-1980, 1957
EXPERIMENTAL STUDIES ON THE EFFECTS OF THE HYPERTONIC GLUCOSE SOLOTION INJECTION INTO THE CAROTID ARTERY UPON GASTRIC MOTILITY
Part I. SPECIAL EFFECTS OF THE HYPERTONIC GLUCOSE SOLUTION INJECTION INTO THE CAROTID ARTERY UPON GASTRIC MOTILITY
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1st Department of Surgery, Osaka Univercity Medical School Hiroshi KAI |
1. The injection of the isotonic glucose solution into the carotid artery shows no significant effects on the gastric motility.
2. The 20% glucose solution injection resulted in a slight fall of gastric pressure and often obliteration of motilities.
This tendency was more remarkable at the higher concentrations of the glucose solution up to 50%. It was noted that an important relationship between the concentration, speed of the injection and the doses of glubose solution.
3. The hypertonic saline solution injection into the carotid artery resulted in a transient inhibition, then followed by a remarkable acceleration.
4. The hypertonic glucose solution injection into the juglar vein resulted in a more slight inhibition compared with the injection into the carotid artery. The intrafemoral artery injection resulted in a transient inhibition, followed by little remarkable inhibition.
From these results I conclude that the inhibition of gastric motility due to the hypertonic glucose solution injection into the carotid artery is special with regard to the following three points: 1. high concentration, 2. administration of glucose, and 3. carotid artery injection.
(author's abstract)
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