J.Jpn. Surg. Soc.. 57(4): 467-486, 1956
CLINICAL AND EXPERIMENTAL STUDIES ON THE POSTOPERATIVE HYPO-NATREMIA AND CHLOREMIA WITH SPECIAL REFERENCE TO THEIR RELATIONS WITH CHANGES IN THE TISSUE ELECTROLYTES AND THE EFFECTS OF THE ADMINISTRATION OF ELECTROLYTES
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Prof. Katsura's Surgical Clinic, Faculty of Medicine, Tohoku University Morio KASAI |
1. The essential postoperative changes in the eleclrolyte balance arc to be found in the appearance of hypo-natremia and chloremia with reduced urinary output of sodium .and chloride and increased urinary output of potassium
2. The principal cause of these changes does not lie in the loss of body electrolytes, nor in the excess of body water.
3. It seems from the results of experimental studies with animals that the postoperative chamges in the plasma electrolytes are determined by the sum of changes in electrolyte contents in all tissues of the body.
4. Post-traumatic accumulation of sodium and chloride and loss of potassium can be observed in the traumatized tissues, nontraumatized muscles and lungs, but little change in the heart and bones. An increase of potassium, howcvrr, can be observed in the liver.
II. Effects of the electrolyte adminislration on the postoperative hypo-natremia and chloremia and on the changes in the tissue eleclrolylcs after cxpcrimenlal traumas were studied, and the following results were obtained:
1. Administration of sodium chloride alone cannot prevent the occurrence of postoperative hypo-natrcmia and chloremia, and intensifies postoperative pulmonary complication. Experimentally, posttraumatic changes in the tissue electrolytes are increased by its administration.
2. Combined administration of potassium chloride and sodium chloride minimizes the postoperative changes in the plasma electrolytes and pulmonary complication. Experimentally, posttraumatic changes in the tissue and plasma electrolytes are reduced by their administration.
(author's abstract)
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