J.Jpn. Surg. Soc.. 56(10): 1292-1307, 1956

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A STUDY ON THE INTESTINAL GAS IN EXPERIMENTALLY PRODUCED ILEUS Part Ⅰ.

The changes in the volume and composition of various gases introduced into the intestinal canal were investigated in rabbits and dogs by Haldane's gas analyzer. The change of intestinaI gas by decomposition test of intestinal contents and by various experimental ileus was also studied and the following results were obtained :
(1) Decomposition of intestinal contents resulted in the formation of H₂S, CH₄, H₂ and CO₂ gases.
(2) Decomposition of intestinal contents, diffusion of blood gases into the intestinal lumen and ingestion of air were contributory as the source of intestinal gas in the obstructed boweI.
It was demonstrated that the first two factors are most significant among them, though they have been ignored in the past.
(3) The volume of intestinal contents in the obstructed boweI has close relationship with the amount of gas formed and also with the composition of the intestinal gas. It tends to produce more gas with larger amount of intestinal contents
(4) Circulatory disturbance of the intestinal wall significantly affects the volume and composition of the gas formed due to the inhibition of the gas absorption from the intestinal wall which results in the increase of gas volume as weII as the gas due to the decomposition of intestinal contents.
(5) It has been considered that N₂ in the intestine derived from the ingested air, however, the amount of N₂ gas diffused through the intestinal wall is quite large, especially in the presence of the circulatory disturbance of the intestinal wall as well as the increase of gas due to the decomposition of intestinal contents.
(6) In cases of simple obstruction of the small intestine there was an increase in intestinal gas, especially due to the decomposition of intestinal contents. The gas composition of the case was H₂S, CO₂, O₂, CH₄, H₂ and N₂.
(7) The same tendency was observed in cases with large bowel obstruction.
(8) In the strangulation ileus, when the affected area is narrow on the amount of its contents is small, no gas formation was observed. On the contrary, when the area is wide, the contents abundant or especially in cases of the strangulated large bowel, a relatively large amount of gas due to the decomposition of contents was formed in the affected area.
(author's abstract)

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