J.Jpn. Surg. Soc.. 56(7): 930-952, 1955

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STUDIES ON THE EXASPERATING SUBSTANCE IN THE SERUM OF ANESTHETIZED RABIT

B. Burstein (1939) manifested the fact that there was in the serum of animal anesthetized with "Nembutal" a substance exasperating the intestinal activity. The author noticed the same fact in the serum of rabits anesthetized wilh sodium pentothal, ether, urcethane, or nitrous oxide (only in the case of oxygen want), so analysed this substance in physiological and pharmacological methods, and found that this was surely choline-like one.
The author measured, further, the level of choline in the serum or every organ of anesthetized rabits, with a chemical improving method which was originated by the author and more efficient than Takayama's method : and The author found certainly the increase of the choline-like substance in the serum and every organ of deep anesthetized rabits.
In another hand, the author probed the decrease of choline-estelase in serum of deep anesthetized rabits.
(author's abstract)

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