J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 7113KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 86(5): 630-639, 1985

Original article

HISTOPATHOLOGICAL STUDY OF PARATHYROID GLAND IN RENAL HYPERPARATHYROIDISM

*) The Organ Transplant Center, Nagoya Second Red Cross Hospital, Nagoya, Japan
**) The Department of Surgery, Aichi Cancer Center, Nagoya, Japan
***) The Department of Pathology, Aichi Cancer Center, Nagoya, Japan
****) Tne Second Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan

Yoshihiro Tominaga*), Hiroshi Takagi**), Harumi Suzuki***), Tatsuhei Kondo****)

From July 1973 to July 1984, 50 patients underwent parathyroidectomy because of secondary hyperparathyroidism due to chronic renal failure. One hundred fifty-eight excised parathyroid glands in 41 of these patients were submitted to the histopathological examinations in the relations to their clinical features which revealed the following findings.
1) Inspite of secondary hyperparathyroidism, eleven of 41 patients showed four unevenly enlarged parathyroid glands with one or two glands weighing less than 100mg.
2) The glands were divided into three adenomas, 101 diffusely and 54 nodulary hyperplastic glands. The nodular type hyperplasia, which had a greater proportion of clear chief cells, vacuolated chief cells, transitional oxyphil cells and oxyphil cells, was more hyperplastic than the diffuse type.
3) The patients with the nodular type showed more advanced clinical features in the secondary hyperparathyroidism.

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