J.Jpn. Surg. Soc.. 54(1): 7-14, 1953
Original article
EXPERIMENTAL STUDIES ON THE CHANGES OF NITROGEN LEVEL OF VARIOUS ORGANS DURING ELECTRIC INJURIES.
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Department of Surgery, Keio Gijuku University School of Medicine Schigeru YAGI |
To investigate the changes of nitrogen non-protein-nitrogen was used as an indicator.
The author has studied on the mechanism of the changing nitrogen and also gave an expla nation to the meaning of the mutual relation between the nitrogen level of various organs.
The author is confident of that a new but important view was obtained in this field as follows:
1. Discharge of aonino-N at all organs increased temporarily and reduced to about normal level 24 hours afterwards, but the discharge of amino-N at the muscles continued long, which causes the increasing amino-N of the blood.
2. The capacity of managenent of amino-N in the liver scarcely decline which has no important elenant causes the increasing amino-N of the blood.
3. The discharge of amino-N at the muscles has no relation with the distruction of the local lesions, but plays an important role in the occurrence of shock, and so the amino-N is suitable for an indicator in shock.
4. The change of amino-N does not parallel with the change of non-protein nitrogen, and so the change of non-protein-nitrogen has a different meaning that the amino-N.
5. Non-protein-nitrogen increases mainly in the hepatic vein and also in the renal veins in the latter stadium of shock.
The causation of increase of nitrogen does not depend on the destruction of the local tissues, but mainly on the disturbances of the renal excretion, Therefore, non-protein-nitrogen is not an indicator to indicate the occurrence of shock but only an indicator to acknowledge the aggravation of the course during shock
(author's abstract)
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