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J.Jpn. Surg. Soc.. 83(9): 907-911, 1982


Report on the annual meeting

AGGRESSIVE THERAPY FOR MALIGNANT TUMOR IN CHILDHOOD

Pediatric Surgical Department,  Chiba University School of Medicin

Naomi Ohnuma, Hideyo Takahashi, Takao Etoh, Masahiro Tanabe, Mayumi Yamamoto, Masahiko Maie, Yonejiro Nagai, Yutaka Kuriyama

Histological vascular invasion in the kidney adjoining primary tumor were examined on 20 cases of Wilms' tumor.
Vascular invasion was classified into 3 grades.
v-0 without any invasion
v-1 with tumor cells observed in the capillaries of the kidney tissue
v-2 with tumor invasions in the venules of the porta renalis, that is the interlobar vein of the kidney. Seven cases of them were classified into v-0, 4 cases v-1, and 9 cases v-2.
The relationship between pulmonary metastases of Wilms' tumor and histological vascular invaion of them were discussed in 16 cases of Wilms' tumor which survived 2 years after operation. There was no pulmonary metastasis in 7 cases of grade v-0. Pulmonary metastases were found in 2 cases among 4 cases of grade v-1 and in 4 cases among 5 cases of grade v-2.
These 6 cases of pulmonary metastases of Wilms' tumor were treated with radiotherapy. All pulmonary metastases were disappeared by whole lung irradiation and small field irradiation. However, we had 2 cases of interstitial pneumonia after whole lung irradiation. These cases were treated with over 300μg/kg Actinomycine D before lung irradiation.


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